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HPLC Solvents

HPLC (High-Performance Liquid Chromatography) solvents, also known as the mobile phase, are fundamental to the success of any HPLC analysis. Their purity, properties, and careful handling are fundamental to getting accurate, reliable, and reproducible results.

Features & Benefits

Exceptional Purity: HPLC solvent purity is paramount. Solvents are rigorously purified to eliminate non-volatile residues, UV-absorbing impurities, particulates, and metal ions. Higher purity levels are available across different grades, including HPLC, Gradient, and LC-MS.

Improved Baseline Stability: Degassed and pure solvents lead to a stable baseline, which is critical for accurate integration of peaks and sensitive detection, especially in gradient methods.

Compliance with Regulatory Standards: For industries like pharmaceuticals and food safety, using specified HPLC-grade solvents is often a regulatory requirement to ensure data integrity and product safety.

Reduced Instrument Downtime: By minimizing contamination and backpressure issues, high-quality solvents contribute to smoother HPLC system operation and reduce the need for maintenance or repairs.

Extended Column Lifespan: Particulate-free and non-reactive solvents prevent column clogging, degradation of the stationary phase, and damage to the sensitive HPLC components, thereby prolonging the life of expensive columns.

Superior Resolution & Enhanced Sensitivity: Precise polarity control in HPLC solvents ensures optimal interaction with the stationary phase, which leads to better separation of complex mixtures and improved peak resolution. Simultaneously, their low UV absorbance allows for the detection of even trace amounts of analytes without background interference, significantly enhancing the method's overall sensitivity.

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